Testing Services
Step Into the Lab:
Our Analytical Standard Production Process
September 17, 2025
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Standards may look like just tiny vials stored in your lab’s freezer, but they play a big role in reliable mycotoxin testing. They’re the benchmarks laboratories rely on to make sure results are dependable. At Trilogy, we make every single one of our standards right here in our U.S. laboratory. That means the process is in our hands from formulation to packaging to shipping.
Why we produce our analytical standards in house.
When it comes to analytical mycotoxin testing, consistency isn’t optional, it’s essential. If analytical standards aren’t produced with an accuracy-driven mindset, test results can’t be trusted no matter how precisely method parameters are followed. Trilogy first began producing analytical standards in-house to fulfill our own mycotoxin laboratories' needs. Fine-tuning our standard production process was one of our first priorities when we opened our laboratory close to 30 years ago. We needed a source of standards that provided unwavering accuracy without having to worry about supply issues and unstable pricing.
Fast forward to our current economic environment, our in-house made standards help keep our mycotoxin testing service prices stable as the industry faces import tariffs and supply issues. By keeping our production in-house in our US facility, we've successfully navigated rising costs internally and that savings is passed on to both our mycotoxin testing clients and our analytical standard customers.
A look at the production process.
Formulation: Every standard starts with carefully sourced materials. Each crystalline mycotoxin is held to strict requirements for appearance, purity, and stability. Our suppliers must meet ISO-defined quality benchmarks for critical components and provide reliable, timely supply. Solvents are selected for both purity and application, always meeting LC/MS grade standards.
We thoroughly verify mycotoxin–solvent interactions and confirm stability across concentrations and solvent blends. When preparing a custom standard, our team reviews every detail of the requested toxin, solvent, and concentration before formulation begins.
Precision Work: The core of this process is Trilogy’s production chemists, who focus exclusively on analytical standards. Trilogy understands that these highly characterized, verified standards are the backbone of the daily work for every analytical laboratory. Crystalline is visually evaluated prior to each use, and stock standards are prepared gravimetrically before checking the prepared dilutions to verify the exact concentrations.
Where applicable, standards are tested spectrophotometrically and further analyzed by HPLC, LC/MS/MS, or both. Each standard must pass the well-defined and documented quality parameters before the standard is accepted for distribution.
Bottling and Labeling: After the analytical standards have passed all quality checks and been verified, the lot is released for bottling. Vials are scrutinized prior to bottling and inspected for any type of visual defect as well as matching the volume of standard to the appropriate vial size to minimize headspace. Vials are filled with precision pipetting, capped and labeled. All labeling is created to make the standards fully traceable.
Every standard is accompanied by a Certificate of Analysis (COA). This document details identity, purity, concentration, measurement uncertainty, stability, and storage conditions. It provides everything needed to use the standard with confidence.
Final Review: As with every product that leaves Trilogy, nothing ships without multiple layers of verification. Analytical results are confirmed by the production chemist, the laboratory analyst, and finally the Chief Scientific Officer. Before shipping, our staff complete a last check of labels, COAs, and packaging integrity.
Only then is a standard cleared to leave our lab and head to yours.
Why in-house production matters.
Producing our standards in-house in our U.S facility means we can keep the production process close, respond quickly to our customers questions and manage pricing responsibly. We're also able to keep a comprehensive inventory of ready-to-ship stock standards but are also flexible enough to quickly produce custom formulation based on a customer's needs.
Explore our full line of stock mycotoxin analytical standards or request a custom standard quote.
