Building Confidence in your In-House Testing Program

Method Selection

• Validate or verify the method with your samples and qualified reference materials
• Validate the sampling and preparation steps – determine whether variability originates from the method itself or from sample handling

Equipment

• Participate in a proficiency sample program to challenge both equipment performance and operator technique
• Review and perform equipment maintenance and software updates for optimal operation

Protocol

• Clearly define the intended use of the method, including the commodities and matrices that have been verified
• Establish decision limits, acceptance criteria, and required actions when results fall outside expected ranges

Training and Troubleshooting

• Document competency for all critical steps of the protocol
• Maintain detailed training records for each analyst
• Challenge analysts on result interpretation, proper documentation, and appropriate handling of out-of-range or unexpected results

System Challenges

• Run daily quality control samples to monitor system performance
• Use matrix relevant reference materials to access accuracy, incorporate naturally contaminated material when possible

Trend Analysis

• Track daily quality control results and investigate any deviations outside established acceptance ranges
• Collaborate with your quality support partners -kit and equipment suppliers, QC material supplier) to review and resolve any abnormal trends

Documentation

• Maintain traceable sample records – including raw data, calculations, deviations, and corrective actions